Overview:
Join Drs. Claudine Blin-Wakkach and Julien Paccou as they present on osteoimmunology and gut microbiome.
Learning Objectives:
- Understand the cellular and molecular mechanisms by which intestinal inflammation and dysbiosis drive bone destruction, in particular in Crohn's disease and osteoporosis.
- Understand the role of osteoclasts in sensing inflammatory signals, with a focus on their heterogeneity.
- Evaluate the clinical consequences of gut inflammation on bone health, including osteoporosis, in patients with inflammatory bowel disease, particularly Crohn's disease.
- Assess the therapeutic potential of probiotics to mitigate bone loss and improve skeletal outcomes.