Tips and Tricks for minimizing side effects

  • Hydration
    • Drink at least two full 16-ounce glasses of water within a few hours before your infusion.
    • Continue drinking plenty of fluids after the treatment.
    • Proper hydration protects your kidneys and helps flush the medication through your system.
  • Pain Relief and Fever Management
    • Take acetaminophen (Tylenol) on the day of your infusion and for about 3 days afterward if your doctor recommends it. This helps reduce flu-like symptoms, fevers, and muscle or joint aches.
    • Avoid nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Motrin) unless your healthcare team specifically approves them. Combining NSAIDs with Reclast can increase the risk of kidney damage.
  • Infusion
    • Request your doctor to prescribe a slow infusion (1 hour if possible) with increased volume of saline and followed by additional saline
  • Supplements and Preparation
    • Take prescribed calcium and vitamin D supplements to prevent your blood calcium levels from dropping too low.

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